Acute Fatty Liver of Pregnancy: Better Understanding of Pathogenesis and Earlier Clinical Recognition Results in Improved Maternal Outcomes
Acute fatty liver of pregnancy (AFLP) is an uncommon disorder affecting women in late pregnancy.It is increasingly recognised as an important cause of preventable maternal mortality across the world.The pathogenic mechanism of AFLP is now better understood; it appears that a compensated defective fatty acid oxidation becomes overt when metabolic st